Infertility affects 1 in 6 couples globally (WHO, 2023). IVF with own eggs costs $2,000–$4,000 abroad versus $12,000–$25,000 in the US. IVF with egg donation — the highest success rate option (55–70% per transfer regardless of age) — costs $4,000–$7,000 abroad versus $25,000–$50,000 in the US. Czech Republic, Spain, Turkey, and Greece are leading fertility treatment destinations.
Medically reviewed by Dr. Murat Ustun, M.D., Founder & Medical Director, Flytocure Healthcare.
Infertility is defined as failure to achieve clinical pregnancy after 12 months of regular unprotected intercourse (6 months for women over 35). It affects both male (40–50% of cases) and female (40–50%) factors, with unexplained infertility accounting for 10–20%. Diagnosis requires: semen analysis (male), hormonal profile + ovarian reserve testing + hysteroscopy/laparoscopy (female). Both partners must be evaluated simultaneously.
| Category | Criteria | Recommended Treatment |
|---|---|---|
| Female — Ovarian factor | Diminished ovarian reserve (low AMH, high FSH), PCOS, premature ovarian failure | IVF with own eggs; egg donation IVF if reserve very low |
| Female — Tubal factor | Blocked fallopian tubes, previous ectopic pregnancy | IVF (bypasses tubes) ± laparoscopic surgery |
| Female — Uterine factor | Fibroids, polyps, Asherman's syndrome, septum | Hysteroscopic surgery → IVF |
| Female — Endometriosis | Mild–moderate: IUI or IVF. Severe: laparoscopic surgery + IVF | IVF (often first-line); laparoscopy if severe |
| Male — Sperm factor | Low count, poor motility, abnormal morphology | ICSI (intracytoplasmic sperm injection) within IVF cycle |
| Male — Severe | Azoospermia (no sperm in ejaculate) | Surgical sperm retrieval (TESE/PESA) + ICSI |
| Unexplained infertility | All tests normal, no identifiable cause | IUI (2–3 cycles) → IVF if unsuccessful |
| Age-related (over 38) | Declining egg quality with age | IVF with own eggs (while possible) → egg donation IVF |
Standard pre-IVF workup: female — Day 2–3 FSH, LH, AMH, oestradiol, prolactin; antral follicle count (transvaginal ultrasound); hysteroscopy or saline sonogram (uterine assessment); STI screening; karyotype if recurrent loss. Male — semen analysis (count, motility, morphology, volume); STI screening; karyotype if severe factor. Most tests can be done with your local GP or fertility clinic and results sent to the overseas clinic.
Top destinations by category: Czech Republic — best for egg donation (large anonymous donor database, €4,500–€7,000, 55–65% LBR). Spain — best regulated egg donation programme, largest European donor network, €6,000–€9,000. Turkey — best cost for own-egg IVF ($2,000–$4,000), egg donation legal since 2022. Greece — strong egg donation programme with identifiable donors available from 2023. North Cyprus — popular for UK patients with no legal restriction on IVF cycles. All four destinations have accredited fertility centres with success rates comparable to leading US clinics.
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