Understanding Nicotine Addiction
Nicotine addiction is the most common substance use disorder globally, affecting over 1.3 billion tobacco users worldwide. Tobacco use remains the leading preventable cause of death, responsible for approximately 8 million deaths annually. Nicotine is one of the most addictive substances known, with dependence developing rapidly and creating powerful physiological and psychological bonds that make quitting extraordinarily difficult. Despite strong motivation to quit — surveys show that 70 percent of smokers want to stop — only 3 to 5 percent of unaided quit attempts succeed, highlighting the need for professional support and evidence-based treatment.
International smoking cessation programs offer a unique advantage: the immersive, distraction-free environment of treatment abroad allows smokers to break free from the environmental triggers and routines associated with their smoking behavior. Combining evidence-based cessation medications with behavioral therapy in an intensive format, delivered in a setting removed from everyday smoking triggers, can achieve quit rates of 40 to 60 percent — far exceeding the success rates of outpatient programs. Moodist Hospital provides intensive smoking cessation programs with experienced addiction medicine physicians and psychologists.

Evidence-Based Cessation Methods
Varenicline (Chantix/Champix) is the most effective single medication for smoking cessation, with quit rates approximately three times higher than placebo. Varenicline works as a partial agonist at nicotinic acetylcholine receptors, simultaneously reducing cravings and blocking the rewarding effects of nicotine. A standard course involves 12 weeks of treatment, with an additional 12 weeks recommended for maintaining abstinence. Bupropion (Wellbutrin/Zyban), an atypical antidepressant, is the second most effective medication, doubling quit rates compared to placebo. It is particularly useful for smokers with co-occurring depression. Both medications are available at international pharmacies at significantly lower cost than in the US.
Nicotine replacement therapy (NRT) provides controlled doses of nicotine without the harmful chemicals in tobacco smoke, reducing withdrawal symptoms and cravings. Combination NRT — using a long-acting form (patch) with a short-acting form (gum, lozenge, inhaler, or nasal spray) — is more effective than single NRT products. Behavioral therapy is essential alongside medication, addressing the psychological and habitual dimensions of smoking. CBT for smoking cessation identifies triggers, develops alternative coping strategies, and builds motivation and confidence for maintaining abstinence.
Intensive cessation programs at international centers provide a comprehensive approach combining medication (varenicline, bupropion, or NRT), individual and group behavioral therapy, stress management and relaxation training, exercise and healthy lifestyle programming, and environmental separation from smoking triggers. The intensive format at Moodist Hospital concentrates treatment into a two to four week period, providing daily support during the critical first weeks when relapse risk is highest.
- Varenicline (Chantix) — most effective single medication, 3x quit rate vs placebo
- Bupropion — doubles quit rate, particularly helpful with co-occurring depression
- Combination NRT — patch plus short-acting form for optimal relief
- CBT — behavioral strategies for triggers, habits, and cravings
- Motivational interviewing — building and maintaining quit motivation
- Mindfulness-based therapy — awareness-based craving management
- Exercise therapy — reducing cravings and managing weight concerns
- Group support — shared experience and mutual encouragement
Cost Comparison by Country
Smoking Cessation Treatment Cost Comparison 2025
| Treatment | USA Cost | Turkey Cost | Savings |
|---|---|---|---|
| Physician Consultation + Plan | $300 - $800 | $100 - $250 | Up to 69% |
| Varenicline (Chantix) 3 months | $1,500 - $3,000 | $300 - $600 | Up to 80% |
| NRT Combination (3 months) | $500 - $1,500 | $150 - $400 | Up to 73% |
| Intensive Cessation Program (2 weeks) | $3,000 - $8,000 | $800 - $2,000 | Up to 75% |
| Residential Cessation + Wellness | $8,000 - $15,000 | $2,000 - $4,000 | Up to 73% |
| Behavioral Therapy (8 sessions) | $1,600 - $4,000 | $400 - $1,000 | Up to 75% |
Combination therapy (medication + behavioral support) produces the highest quit rates. International pharmacies offer cessation medications at significantly lower cost.
Ready to quit smoking for good? Get free quotes from treatment centers offering intensive smoking cessation programs with medication and behavioral support.
Get Free QuoteTop Smoking Cessation Centers
Moodist Hospital offers intensive smoking cessation programs combining medication management, behavioral therapy, and wellness programming. The hospital's addiction medicine team assesses each patient's smoking history, nicotine dependence level, prior quit attempts, and co-occurring conditions to develop an individualized cessation plan. Acıbadem Maslak Hospital and Memorial Şişli Hospital provide smoking cessation services within their preventive medicine and pulmonary departments.

Staying Smoke-Free Long-Term
Long-term success after an intensive cessation program depends on continued medication use (most evidence supports 12 to 24 weeks of medication), ongoing behavioral strategy application, managing triggers and high-risk situations, addressing weight gain concerns with exercise and nutrition, building a smoke-free social environment, and utilizing follow-up support. Relapse is common but does not represent failure — most successful quitters have made multiple attempts before achieving lasting abstinence.
I had tried patches, gum, apps, and willpower for 20 years. The two-week intensive cessation program at Moodist Hospital combined Champix with daily therapy in a smoke-free environment. Being away from my usual triggers made all the difference. The program cost $1,800 including medication. I have been smoke-free for over a year — my only regret is not doing this sooner.
George T., smoking cessation patient from the UK
Frequently Asked Questions
What is the most effective way to quit smoking?
Combination therapy (medication plus behavioral support) produces the highest quit rates. Varenicline combined with counseling achieves 6-month quit rates of 40-60%. Intensive programs that provide daily support during the critical first 2 weeks, like those offered at international cessation centers, further improve success rates by addressing both physical and psychological dependence simultaneously.
Should I use a patch before arriving for treatment?
Discuss this with the treatment center before traveling. Some programs prefer patients arrive still smoking so that medication and cessation can be initiated under medical supervision. Others may recommend starting NRT before arrival. Your treatment center will provide specific pre-arrival instructions based on their protocol.
Will I gain weight after quitting?
Average weight gain after quitting is 5-10 pounds, primarily due to metabolic changes and increased appetite. Treatment programs address this concern through exercise programming, nutritional guidance, and medication (both varenicline and bupropion are associated with less weight gain). The health benefits of quitting far outweigh any modest weight gain.
How long should I take cessation medication?
Standard courses are 12 weeks, with evidence supporting extended use of 12-24 weeks for optimal quit rates. Some patients benefit from longer medication courses. Your cessation physician will recommend the appropriate duration based on your dependence level, prior quit attempts, and individual response to medication.